Conventionally, chitosans are derived from shrimp and other crustacean shells. Biotechnology offers an alternative route to produce chitosans and more importantly, specific chitosan structures tailored to the needs of a diversity of industries.
However, for biotech chitosans and products thereof to be commercialised, legislation should not create a burden. Here, the requirements of the EU regulatory framework have been analysed for the entire chain from research to development and production of several potential applications including nanomaterials.
The animal or biotechnological origin leads to specific requirements in production of the raw material. No EU legislation dedicated to nanomaterials has been adopted. Instead, products are governed under the respective existing product legislation subject to extra requirements for safety assessment.
 2-Thio-UTP |
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| B7984-.1 | ApexBio | 100 µl (100 mM) | EUR 902.4 |
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Description: Modified Nucleotides |
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 2-Thio-CTP |
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| B7988-.01 | ApexBio | 10 µl (100 mM) | EUR 126.4 |
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Description: Modified Nucleotides |
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2-Thio-CTP |
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| B7988-.05 | ApexBio | 50 µl (100 mM) | EUR 532.8 |
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Description: Modified Nucleotides |
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2-Thio-CTP |
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| B7988-.1 | ApexBio | 100 µl (100 mM) | EUR 902.4 |
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Description: Modified Nucleotides |
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 2-Thio-PAF |
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| HY-101263 | MedChemExpress | 10mg（46.32 mM * 400 uL in Ethanol） | EUR 687.24 |
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Description: 2-Thio-PAF, a synthetic analog of PAF, is used in a colorimetric assay for PAF acetylhydrolases[1]. |
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2-Thio-PAF |
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| MBS5771797-5mg | MyBiosource | 5mg | EUR 915 |
2-Thio-PAF |
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| MBS5771797-5x5mg | MyBiosource | 5x5mg | EUR 3970 |
2-Thio-UTP |
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| NU-1151L | Jena Bioscience GmbH | 5 x 10µl | EUR 150.4 |
2-Thio-UTP |
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| NU-1151S | Jena Bioscience GmbH | 10µl | EUR 41.26 |
2-Thio-PAF |
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| T19104-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: 2-Thio-PAF |
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2-Thio-PAF |
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| T19104-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: 2-Thio-PAF |
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2-Thio-PAF |
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| T19104-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: 2-Thio-PAF |
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2-Thio-PAF |
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| T19104-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: 2-Thio-PAF |
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2-Thio-PAF |
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| T19104-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: 2-Thio-PAF |
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 2-Thio-dTTP |
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| B8100-.01 | ApexBio | 10ul (100 mM) | EUR 88 |
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Description: Modified Nucleotides |
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2-Thio-dTTP |
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| B8100-.05 | ApexBio | 50ul (100 mM) | EUR 362.4 |
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Description: Modified Nucleotides |
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2-Thio-dTTP |
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| B8100-.1 | ApexBio | 100ul (100 mM) | EUR 651.2 |
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Description: Modified Nucleotides |
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 2-Thio-dCTP |
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| B8104-.01 | ApexBio | 10ul (100 mM) | EUR 88 |
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Description: Modified Nucleotides |
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2-Thio-dCTP |
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| B8104-.05 | ApexBio | 50ul (100 mM) | EUR 362.4 |
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Description: Modified Nucleotides |
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2-Thio-dCTP |
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| B8104-.1 | ApexBio | 100ul (100 mM) | EUR 651.2 |
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Description: Modified Nucleotides |
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 2-Thio 2'-Deoxyuridine |
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| MBS6108537-10mg | MyBiosource | 10(mg | EUR 610 |
2-Thio 2'-Deoxyuridine |
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| MBS6108537-5x10mg | MyBiosource | 5x10mg | EUR 2600 |
2-Thio 2'-Deoxyuridine |
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| T350100 | Toronto Research Chemicals | 2.5mg | EUR 1453 |
 2-Quinolineacetamide, thio- |
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| MBS5779013-INQUIRE | MyBiosource | INQUIRE | Ask for price |
2-Quinolineacetamide, thio- |
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| T29374-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: 2-Quinolineacetamide, thio- |
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2-Quinolineacetamide, thio- |
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| T29374-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: 2-Quinolineacetamide, thio- |
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2-Quinolineacetamide, thio- |
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| T29374-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: 2-Quinolineacetamide, thio- |
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2-Quinolineacetamide, thio- |
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| T29374-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: 2-Quinolineacetamide, thio- |
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2-Quinolineacetamide, thio- |
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| T29374-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: 2-Quinolineacetamide, thio- |
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 2-Thio-2'-deoxy Cytidine |
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| MBS6056856-10mg | MyBiosource | 10(mg | EUR 610 |
2-Thio-2'-deoxy Cytidine |
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| MBS6056856-5x10mg | MyBiosource | 5x10mg | EUR 2600 |
 2-Thio-2’-deoxy Cytidine |
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| T350050 | Toronto Research Chemicals | 250mg | EUR 3000 |
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Description: 169557-13-5 |
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2-Thio-2’-deoxy Cytidine |
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| TRC-T350050-250MG | Toronto Research Chemicals | 250 mg | Ask for price |
 6-Thio-2'-Deoxyguanosine |
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| HY-18762 | MedChemExpress | 10mM/1mL | EUR 389.62 |
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Description: 6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. |
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6-Thio-2'-Deoxyguanosine |
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| T6746-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: 6-Thio-2'-Deoxyguanosine |
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6-Thio-2'-Deoxyguanosine |
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| T6746-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: 6-Thio-2'-Deoxyguanosine |
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6-Thio-2'-Deoxyguanosine |
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| T6746-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: 6-Thio-2'-Deoxyguanosine |
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6-Thio-2'-Deoxyguanosine |
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| T6746-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: 6-Thio-2'-Deoxyguanosine |
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6-Thio-2'-Deoxyguanosine |
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| T6746-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: 6-Thio-2'-Deoxyguanosine |
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 2-Thio-6-Oxypurine_x000D__x000D_ |
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| T11515 | Pfaltz & Bauer | 1G | EUR 145.95 |
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Description: CAS N° 2487-40-3 |
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) 2-Thio-UTP (tetrasodium) |
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| HY-108650 | MedChemExpress | Get quote | Ask for price |
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Description: 2-Thio-UTP tetrasodium is a potent P2Y2, P2Y4 and P2Y6 agonist, which an be used for the research of cancer[1]. |
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) Thio-oxidized Coenzyme I (Thio-NAD+) |
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| N8210 | Solarbio Life Science |
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 2-Thio-dT 2 µmol scale |
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| 26-6537-03 | Gene Link | 1 Each | Ask for price |
 2 µmol scale) Thio-2-rU (s2U) 2 µmol scale |
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| 27-6537-03 | Gene Link | 1 Each | Ask for price |
thio]-2-propanone) 1-[(2-Chlorophenyl)thio]-2-propanone |
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| MBS6059378-500mg | MyBiosource | 500(mg | EUR 610 |
1-[(2-Chlorophenyl)thio]-2-propanone |
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| MBS6059378-5x500mg | MyBiosource | 5x500mg | EUR 2600 |
 Thio-NAD |
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| 9483-1000 | Biovision | each | EUR 1299.6 |
Thio-NAD |
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| 9483-250 | Biovision | each | EUR 627.6 |
Thio-NAD |
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| 9483-50 | Biovision | each | EUR 235.2 |
 Thio-ITP |
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| HY-115755 | MedChemExpress | Get quote | Ask for price |
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Description: Thio-ITP (6-Thioinosine 5′-triphosphate) is an RNA polymerase activity competitive inhibitor. Thio-ITP has a high apparent affinity for the polymerases (RNA polymerase I Ki: 40.9 μM; RNA polymerase II Ki: 38.0 μM)[1]. |
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Thio-ITP |
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| MBS5800620-5mg | MyBiosource | 5(mg | EUR 915 |
Thio-ITP |
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| MBS5800620-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
Thio-ITP |
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| T40359-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: Thio-ITP |
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Thio-ITP |
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| T40359-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: Thio-ITP |
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Thio-ITP |
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| T40359-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: Thio-ITP |
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Thio-ITP |
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| T40359-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: Thio-ITP |
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Thio-ITP |
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| T40359-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: Thio-ITP |
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 Thio-TEPA |
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| B3742-100 | ApexBio | 100mg | EUR 192 |
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Description: DNA Damage/DNA Repair|DNA Alkylating |
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Thio-TEPA |
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| B3742-1000 | ApexBio | 1 g | EUR 61 |
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Description: alkylating agent used to treat cancer |
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Thio-TEPA |
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| B3742-25 | ApexBio | 25mg | EUR 72 |
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Description: DNA Damage/DNA Repair|DNA Alkylating |
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Thio-TEPA |
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| B3742-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 76 |
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Description: DNA Damage/DNA Repair|DNA Alkylating |
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Thio-TEPA |
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| B3742-50 | ApexBio | 50mg | EUR 108 |
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Description: DNA Damage/DNA Repair|DNA Alkylating |
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 Thio-NADP |
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| HY-154924 | MedChemExpress | Get quote | Ask for price |
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Description: Thio-NADP (S-NADP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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 Thio-NADH |
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| HY-154925 | MedChemExpress | Get quote | Ask for price |
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Description: Thio-NADH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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Thio-TEPA |
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| HY-17574 | MedChemExpress | 100mg | EUR 151.52 |
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Description: Thio-TEPA is a DNA alkylating agent, with antitumor activity. |
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Thio-TEPA |
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| MBS3604840-100mg | MyBiosource | 100mg | EUR 200 |
Thio-TEPA |
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| MBS3604840-200mg | MyBiosource | 200mg | EUR 225 |
Thio-TEPA |
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| MBS3604840-5x200mg | MyBiosource | 5x200mg | EUR 695 |
Thio-TEPA |
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| T1250-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: Thio-TEPA |
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Thio-TEPA |
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| T1250-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: Thio-TEPA |
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Thio-TEPA |
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| T1250-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: Thio-TEPA |
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Thio-TEPA |
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| T1250-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: Thio-TEPA |
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Thio-TEPA |
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| T1250-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: Thio-TEPA |
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thio)benzoic Acid) 2-((2-Isopropylphenyl)thio)benzoic Acid |
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| I873908 | Toronto Research Chemicals | 100mg | EUR 87 |
2-((2-Isopropylphenyl)thio)benzoic Acid |
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| TRC-I873908-100MG | Toronto Research Chemicals | 100 mg | Ask for price |
2-((2-Isopropylphenyl)thio)benzoic Acid |
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| TRC-I873908-250MG | Toronto Research Chemicals | 250 mg | Ask for price |
2-((2-Isopropylphenyl)thio)benzoic Acid |
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| TRC-I873908-50MG | Toronto Research Chemicals | 50 mg | Ask for price |
thio]acetic Acid) 2-[(Diphenylmethyl)thio]acetic Acid |
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| D491830 | Toronto Research Chemicals | 500mg | EUR 110 |
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Description: 63547-22-8 |
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2-[(Diphenylmethyl)thio]acetic Acid |
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| TRC-D491830-500MG | Toronto Research Chemicals | 500 mg | Ask for price |
 thiO Antibody |
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| 1-CSB-PA521738LA01BRJ | Cusabio |
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Description: A polyclonal antibody against thiO. Recognizes thiO from Bacillus subtilis. This antibody is Unconjugated. Tested in the following application: ELISA |
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thio]adenosine) 2-[(3,3,3-Trifluoropropyl)thio]adenosine |
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| T792665 | Toronto Research Chemicals | 100mg | EUR 1800 |
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Description: 163706-51-2 |
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2-[(3,3,3-Trifluoropropyl)thio]adenosine |
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| TRC-T792665-100MG | Toronto Research Chemicals | 100 mg | Ask for price |
) Thio-Nicotinamide-Adenine Dinucleotide, Oxidized (Thio-NAD) |
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| MBS682168-1g | MyBiosource | 1g | EUR 785 |
) Thio-Nicotinamide-Adenine Dinucleotide, Reduced (Thio-NADH) |
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| MBS682171-100mg | MyBiosource | 100mg | EUR 540 |
Thio-Nicotinamide-Adenine Dinucleotide, Oxidized (Thio-NAD) |
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| MBS682174-100mg | MyBiosource | 100mg | EUR 380 |
 Ethyl 2-thio-α-D-fructofuranoside |
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| GC8803 | Glentham Life Sciences | 250mg | EUR 1263.27 |
Ethyl 2-thio-α-D-fructofuranoside |
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| GC8803-1 | Glentham Life Sciences | 1 | EUR 857.7 |
Ethyl 2-thio-α-D-fructofuranoside |
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| GC8803-2 | Glentham Life Sciences | 2 | EUR 1379.7 |
Ethyl 2-thio-α-D-fructofuranoside |
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| GC8803-250 | Glentham Life Sciences | 250 | EUR 344.8 |
Ethyl 2-thio-α-D-fructofuranoside |
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| GC8803-500 | Glentham Life Sciences | 500 | EUR 522 |
 Ethyl 2-thio-β-D-fructofuranoside |
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| GC2672 | Glentham Life Sciences | 100mg | EUR 1083.98 |
Ethyl 2-thio-β-D-fructofuranoside |
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| GC2672-1 | Glentham Life Sciences | 1 | EUR 1183.8 |
Ethyl 2-thio-β-D-fructofuranoside |
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| GC2672-100 | Glentham Life Sciences | 100 | EUR 242.4 |
Ethyl 2-thio-β-D-fructofuranoside |
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| GC2672-250 | Glentham Life Sciences | 250 | EUR 400.9 |
Ethyl 2-thio-β-D-fructofuranoside |
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| GC2672-500 | Glentham Life Sciences | 500 | EUR 680.5 |
 2-Thio-dT 1 µmol scale |
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| 26-6537-01 | Gene Link | 1 Each | Ask for price |
 2-Thio-dT 10 µmol scale |
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| 26-6537-10 | Gene Link | 1 Each | Ask for price |
 2-Thio-dT 15 µmol scale |
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| 26-6537-15 | Gene Link | 1 Each | Ask for price |
 2-Thio-dT 25 nmol scale |
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| 26-6537-25 | Gene Link | 1 Each | Ask for price |
 2-Thio-dT 200 nmol scale |
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| 26-6537-02 | Gene Link | 1 Each | Ask for price |
 2-Thio-dT 50 nmol scale |
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| 26-6537-05 | Gene Link | 1 Each | Ask for price |
-2-thio-) Urea, 1-(L-glucosyl)-2-thio- |
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| MBS5784483-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Urea, 1-(L-glucosyl)-2-thio- |
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| T35002-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: Urea, 1-(L-glucosyl)-2-thio- |
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Urea, 1-(L-glucosyl)-2-thio- |
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| T35002-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: Urea, 1-(L-glucosyl)-2-thio- |
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Urea, 1-(L-glucosyl)-2-thio- |
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| T35002-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: Urea, 1-(L-glucosyl)-2-thio- |
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Urea, 1-(L-glucosyl)-2-thio- |
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| T35002-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: Urea, 1-(L-glucosyl)-2-thio- |
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Urea, 1-(L-glucosyl)-2-thio- |
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| T35002-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: Urea, 1-(L-glucosyl)-2-thio- |
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 2 µmol scale) Thio-4-rU (s4U) 2 µmol scale |
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| 27-6445-03 | Gene Link | 1 Each | Ask for price |
 1 µmol scale) Thio-2-rU (s2U) 1 µmol scale |
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| 27-6537-01 | Gene Link | 1 Each | Ask for price |
 200 nmol scale) Thio-2-rU (s2U) 200 nmol scale |
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| 27-6537-02 | Gene Link | 1 Each | Ask for price |
 50 nmol scale) Thio-2-rU (s2U) 50 nmol scale |
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| 27-6537-05 | Gene Link | 1 Each | Ask for price |
 5 µmol scale) Thio-2-rU (s2U) 5 µmol scale |
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| 27-6537-06 | Gene Link | 1 Each | Ask for price |
 25 nmol scale) Thio-2-rU (s2U) 25 nmol scale |
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| 27-6537-25 | Gene Link | 1 Each | Ask for price |
 5 µmol scale) Thio-2-dT (S2dT) 5 µmol scale |
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| 26-6537-06 | Gene Link | 1 Each | Ask for price |
 2 µmol scale) Thio-4-dT (S4dT) 2 µmol scale |
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| 26-6538-03 | Gene Link | 1 Each | Ask for price |
thio]acetic Acid Hydrazide) 2-[(2-Nitrophenyl)thio]acetic Acid Hydrazide |
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| N506005 | Toronto Research Chemicals | 1g | EUR 1800 |
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Description: 4871-40-3 |
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2-[(2-Nitrophenyl)thio]acetic Acid Hydrazide |
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| TRC-N506005-1G | Toronto Research Chemicals | 1 g | Ask for price |
 6-thio-dG |
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| 561277 | MedKoo Biosciences | 5.0mg | EUR 250 |
 6-Thio-dG |
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| B6009-10 | ApexBio | 10 mg | EUR 93.6 |
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Description: DNA Damage/DNA Repair|Telomerase |
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6-Thio-dG |
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| B6009-25 | ApexBio | 25 mg | EUR 278.4 |
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Description: DNA Damage/DNA Repair|Telomerase |
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6-Thio-dG |
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| B6009-5 | ApexBio | 5 mg | EUR 86.4 |
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Description: DNA Damage/DNA Repair|Telomerase |
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6-Thio-dG |
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| B6009-50 | ApexBio | 50mg | EUR 436.8 |
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Description: DNA Damage/DNA Repair|Telomerase |
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6-Thio-dG |
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| MBS3841242-10mg | MyBiosource | 10mg | EUR 170 |
6-Thio-dG |
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| MBS3841242-25mg | MyBiosource | 25mg | EUR 245 |
6-Thio-dG |
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| MBS3841242-50mg | MyBiosource | 50mg | EUR 380 |
6-Thio-dG |
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| MBS3841242-5x50mg | MyBiosource | 5x50mg | EUR 1710 |
6-Thio-dG |
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| MBS3609102-50mg | MyBiosource | 50mg | EUR 440 |
6-Thio-dG |
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| MBS3609102-5x50mg | MyBiosource | 5x50mg | EUR 1665 |
thio]propanoic Acid) 2-[(4-Methylphenyl)thio]propanoic Acid |
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| M339405 | Toronto Research Chemicals | 100mg | EUR 69 |
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Description: 17431-98-0 |
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2-[(4-Methylphenyl)thio]propanoic Acid |
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| TRC-M339405-10MG | Toronto Research Chemicals | 10 mg | Ask for price |
2-[(4-Methylphenyl)thio]propanoic Acid |
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| TRC-M339405-100MG | Toronto Research Chemicals | 100 mg | Ask for price |
2-[(4-Methylphenyl)thio]propanoic Acid |
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| TRC-M339405-50MG | Toronto Research Chemicals | 50 mg | Ask for price |
 4-Thio-UTP |
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| B7978-.01 | ApexBio | 10 µl (100 mM) | EUR 153.6 |
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Description: Modified Nucleotides |
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4-Thio-UTP |
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| B7978-.05 | ApexBio | 50 µl (100 mM) | EUR 675.2 |
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Description: Modified Nucleotides |
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4-Thio-UTP |
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| B7978-.1 | ApexBio | 100 µl (100 mM) | EUR 1225.6 |
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Description: Modified Nucleotides |
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 6-Thio-GTP |
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| NU-1106L | Jena Bioscience GmbH | 5 x 150µl | EUR 349.05 |
6-Thio-GTP |
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| NU-1106S | Jena Bioscience GmbH | 150µl | EUR 119.15 |
 6-Thio-GDP |
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| NU-1120L | Jena Bioscience GmbH | 5 x 50µl | EUR 332.26 |
6-Thio-GDP |
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| NU-1120S | Jena Bioscience GmbH | 50µl | EUR 113.48 |
 6-Thio-GMP |
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| NU-1121L | Jena Bioscience GmbH | 5 x 150µl | EUR 349.05 |
6-Thio-GMP |
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| NU-1121S | Jena Bioscience GmbH | 150µl | EUR 119.15 |
 4-Thio-UMP |
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| NU-1154L | Jena Bioscience GmbH | 5 x 50µl | EUR 332.26 |
4-Thio-UMP |
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| NU-1154S | Jena Bioscience GmbH | 50µl | EUR 113.48 |
 4-Thio-UDP |
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| NU-1155L | Jena Bioscience GmbH | 5 x 20µl | EUR 332.26 |
4-Thio-UDP |
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| NU-1155S | Jena Bioscience GmbH | 20µl | EUR 113.48 |
4-Thio-UTP |
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| NU-1156L | Jena Bioscience GmbH | 5 x 10µl | EUR 266.23 |
4-Thio-UTP |
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| NU-1156S | Jena Bioscience GmbH | 10µl | EUR 77.94 |
thio]acetic Acid-d10) 2-[(Diphenylmethyl)thio]acetic Acid-d10 |
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| D491832 | Toronto Research Chemicals | 50mg | EUR 150 |
2-[(Diphenylmethyl)thio]acetic Acid-d10 |
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| MBS6110381-5mg | MyBiosource | 5(mg | EUR 485 |
2-[(Diphenylmethyl)thio]acetic Acid-d10 |
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| MBS6110381-5x5mg | MyBiosource | 5x5(mg | EUR 2025 |
2-[(Diphenylmethyl)thio]acetic Acid-d10 |
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| TRC-D491832-50MG | Toronto Research Chemicals | 50 mg | Ask for price |
2-[(Diphenylmethyl)thio]acetic Acid-d10 |
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| TRC-D491832-5MG | Toronto Research Chemicals | 5 mg | Ask for price |
While a knowledge gap exists on hazards related to nanomaterials in general, there is a need to establish realistic regulatory study designs to assess the safety of specific products. Furthermore, as many of the existing chitosan applications are not considered nanomaterials, it would be discriminatory to treat biotechnology derived products differently.
